Scott Freda on Instagram: "Liver flap” is a grave sign indicating severe disease and a poor prognosis, especially in women with alcoholic cirrhosis, The “liver flap,” medically known as asterixis, is a clinical sign of metabolic encephalopathy, most commonly hepatic encephalopathy (HE), which is associated with late-stage, decompensated liver disease, including alcoholic cirrhosis. Its presence in a patient with liver disease is a major sign of decompensated cirrhosis and hepatic encephalopathy,