Retinol | C20H30O | CID 445354 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

Retinol is an essential compound in the cycle of light-activated chemical reactions called the "visual cycle" that underlies vertebrate vision. Retinol is converted by the protein RPE65 within the pigment epithelium of the retina into 11-cis-retinal.

When retinol reaches a keratinocyte, it enters its interior and binds to an appropriate receptor. There are four groups of receptors with high affinity towards retinol (CRBP) [4, 5]. Retinol stimulates the cellular activity of keratinocytes, fibroblasts, melanocytes and Langerhans cells.

The retinol structure contains a substituted β-ionone ring with a side chain of three isoprenoid units linked at the 6-position of the β-inone ring (Figure 6.1). The human body makes trans -retinol from β-carotene available in carrots.

A, also called retinol (the active form of vitamin A), is a fat-soluble vitamin with a molecular formula C20H30O and molar mass: 286.45 g/mol. The IUPAC name is 3,7-dimethyl-9-...

The retinol structure shown in Figure 1 is all- trans -retinol, as all of the double bonds are in the trans configuration. Many cis isomers also occur. Two important examples are 11- cis -retinal, which is required for vision (see Figure1), and 13- cis -retinoic acid (or isotretinoin), which is used as an anti-acne drug.

The ring structure of retinol ((i-ionone), or the more unsaturated ring in 3-dehydroretinol (dehydro-P-ionone), is essential for activity hydrogenation destroys biological activity. Of all known derivatives, all-/ran,v-retinol and its aldehyde, retinal, exhibit the greatest biological potency in vivo 3-dehydroretinol has about 40% of the ...

Retinol contains total 51 bond (s); 21 non-H bond (s), 5 multiple bond (s), 5 rotatable bond (s), 5 double bond (s), 1 six-membered ring (s), 1 hydroxyl group (s), and 1 primary alcohol (s). Learn more about chemical structure at Mol-Instincts.

Chemical analyses have identified specific organic molecular structures and systems, including protoporphyrins and conjugated C=C bonds, as pivotal components in molecular photosensitivity.

Retinoids comprise a group of compounds each composed of three basic parts: a trimethylated cyclohexene ring that is a bulky hydrophobic group, a conjugated tetraene side chain that functions...