The intestinal mucosal barrier, also referred to as intestinal barrier, refers to the property of the intestinal mucosa that ensures adequate containment of undesirable luminal contents within …

In this article I review our current understanding of the mechanisms that regulate intestinal barrier integrity, and discuss the hypothesis that the mucosal barrier can shape pro-inflammatory...

The gastrointestinal mucosa constitutes a critical barrier where millions of microbes and environmental antigens come in close contact with the host immune system. Intestinal barrier …

Mucosal surfaces are lined by epithelial cells. These cells establish a barrier between sometimes hostile external environments and the internal milieu. However, mucosae are also responsible …

Mucosal barriers separate self from non-self and are essential for life. These barriers, which are the first line of defense against external pathogens, are formed by epithelial cells and the …

In this context, we will discuss the mucosal barrier system, which consists of epithelial cell-derived chemical and physical barrier molecules and plasma cell-derived immunoglobulin A (IgA), and …

Jan 15, 2017 · Mucosal barriers separate self from non-self and are essential for life. These barriers, which are the first line of defense against external pathogens, are formed by epithelial …

Mar 11, 2025 · The intestinal barrier serves as a boundary between the mucosal immune system in the lamina propria and the external environment of the intestinal lumen, which contains a …

The intestinal mucosal barrier is an important line of defense for the body, including mechanical, chemical, biological, and immune barriers. The integrity of the intestinal mucosal barrier …

Apr 5, 2016 · Therefore, regulation of the barrier function of epithelial cells by regulating the expression and localization of TJ proteins is a potential new target for the treatment of these …