Watch all of the highlights from the Detroit Lions' 40-34 Week 17 victory over the San Francisco 49ers. Watch Detroit Lions quarterback Jared Goff connect with San Francisco 49ers fullback Kyle ...

WATCH:Lions vs. 49ers LIVE on Fubo The Lions are currently the No. 1 seed in the NFC with two games remaining. That said, they're not locked into that spot. Detroit is tied with the Vikings at 13 ...

Here's everything you need to know before the San Francisco 49ers take on the Detroit Lions in Week 1 of the 2021 NFL season.

When this rematch of last year’s NFC Championship between the Detroit Lions and San Francisco 49ers was announced during the offseason, it seemed destined to have playoff implications.