See related article at A crisis of communicable diseases is unfolding in North America, just as Canada’s health systems’ responses are being hampered by the dismantling of public health and research ...

Iron deficiency and iron deficiency anemia are common during pregnancy and are associated with adverse outcomes Prenatal iron deficiency occurs in more than 30% of pregnancies in Canada. 1 It has been ...

In research published in this issue of CMAJ, Mah and colleagues summarize clinicians’ experiences of providing care for patients whose presenting illness is not acute and for whom admission to ...

A pregnant, primiparous 32-year-old woman at 28 weeks’ gestation presented for a routine prenatal visit. Blood work showed thrombocytopenia with platelet count of 60 (reference range 130–380) × 109/L.

Azathioprine and myelosuppression Azathioprine is a commonly used immunosuppressant, and is approved by Health Canada for the treatment of rheumatoid arthritis and for the prevention of graft ...

KEY POINTS Genitourinary syndrome of menopause (GSM) is common and can be treated with over-the-counter vaginal lubricants or supplementation with vaginal estrogen. Vaginal energy devices (such as CO2 ...

KEY POINTS Multifactorial early-pregnancy screening for preeclampsia can identify most patients at risk, particularly of early-onset, severe disease. Prophylaxis with acetylsalicylic acid (ASA) can ...

A meta-analysis of 20 000 people from the general population who were patch tested confirmed a 20% prevalence of contact allergy, with nickel being the most common allergen (11.4%). 1 Prevalence is ...

Bell palsy is an idiopathic weakness or paralysis of the face of peripheral nerve origin, with acute onset. It affects 20–30 persons per 100 000 annually, and 1 in 60 individuals will be affected over ...

Randomized clinical trials play a pivotal role in answering questions about the superiority of competing treatments. They are initiated not because a particular investigator is unsure of the treatment ...

As a specialist in internal medicine, Brian Harley explores the intricate terrain of the human body. But as a writer and amateur historian, he turns his attention to the rugged landscape of the place ...