Purpose— Our goal is to provide an overview of the current evidence about components of the evaluation and treatment of adults with acute ischemic stroke. The intended audience is physicians and other ...

Focal adhesion kinase (FAK) is a ubiquitously expressed cytoplasmic tyrosine kinase strongly activated by integrins and neurohumoral factors. Previous studies have shown that cardiac FAK activity is ...

Background— Heart failure with preserved left ventricular (LV) ejection fraction (EF) is increasingly recognized and usually referred to as diastolic heart failure (DHF). Its pathogenetic mechanism r ...

The science of cardiology has evolved parallel to most medical sciences, first emphasizing anatomy, then physiology, and now molecular biology. In the 1960s, when it had become obvious that effective ...

Background— Intake of trans fatty acids is associated with increased risk of coronary heart disease. Whether different classes of trans fatty acids show similar associations is unclear. We previously ...

The publication of the 2023 American Heart Association (AHA) Guidelines for the Management of Aneurysmal Subarachnoid Hemorrhage represents a milestone in the evolving landscape of cerebrovascular ...

While mechanical thrombectomy (MT) is proven to be lifesaving and disability sparing, there remains a disparity in its access in low- to middle-income countries. We hypothesized that team-based MT ...

The Elective PCI in Outpatient Study (EPOS) was designed to evaluate the safety and feasibility of discharge the same day as PCI by testing the hypothesis that patients requiring extended observation ...

Stroke is a leading cause of death that disproportionately affects women. Treating carotid stenosis with carotid artery stenting (CAS) or carotid endarterectomy (CEA) can prevent ischemic stroke. Yet, ...

Background— BAY 41-2272 is a recently introduced novel orally available agent that directly stimulates soluble guanylate cyclase (sGC) and sensitizes it to its physiological stimulator, nitric oxide.

Relationships Between Low-Density Lipoprotein Particle Size, Plasma Lipoproteins, and Progression of Coronary Artery Disease ...

Background— The platelet glycoprotein IIb/IIIa receptor inhibitor abciximab, a monoclonal antibody, has been shown to improve early and late outcomes among diabetic patients undergoing percutaneous c ...