Lenyn Sosa hit a tying two-run homer with two outs in the ninth inning, but the Chicago White Sox lost their 118th game when ...

Fernando Tatis Jr.'s run-scoring hit leading off the 10th lifted the Padres to a 3-2 victory over the White Sox Friday.

The San Diego Padres (88-66) take on the Chicago White Sox (36-118), who will be trying to halt a three-game losing streak, ...

Manny Machado and the San Diego Padres square off against the Chicago White Sox and starter Chris Flexen on Saturday at 8:40 ...

ET, Jurickson Profar and the San Diego Padres (88-66) face Andrew Vaughn and the Chicago White Sox (36-118) at PETCO Park.

What to look for from the top San Diego Padres and Chicago White Sox players and how to watch the game as they face off on ...

Oddsmakers have listed player props for Jurickson Profar, Andrew Vaughn and others when the San Diego Padres host the Chicago ...

The Chicago White Sox (36-118) bring a three-game losing streak into a road contest against the San Diego Padres (88-66) at 8 ...

Preview the Sept. 21 matchup between the San Diego Padres and Chicago White Sox with odds over/under, game spread, betting ...

Preview the Sept. 21 matchup between the San Diego Padres and Chicago White Sox with recent trends, how to watch, livestream ...

Fernando Tatis Jr. wins game with double leading off the 10th inning; Joe Musgrove throws six scoreless innings ...

The San Diego Padres (87-66), led by Jurickson Profar, host Andrew Vaughn and the Chicago White Sox (36-117) at 9:40 PM ET on ...