The FDA laid out a three-year roadmap to phase out animal toxicity testing in drug research. In addition to organoids and lab ...

Monoclonal antibody (mAb): Originally, mAbs were antibodies produced from a single B lymphocyte. Genetic manipulation now allows genes from multiple sources of B lymphocytes (e.g., mouse and human ...

The FDA is moving away from requiring animal models for investigational new drug (IND) applications for new monoclonal ...

A key theme at the AD/PD 2025 has been the safety profile of DMTs, focusing on the issue of ARIA, a significant side effect ...

This is a groundbreaking step toward advancing public health by using more effective and human-relevant methods instead of ...

The Biden administration's FDA "seemed to be inert" on the issue, and even "obstructionist," after Congress removed mandatory animal testing, longtime group leader says. Bill to ban research funding ...

Sanofi (NASDAQ:SNY) announced Tuesday that its TIDE-Asthma Phase 2 study for its T-cell-depleting monoclonal antibody ...

Antibodies that interfere with IL-6 function Tocilizumab is a monoclonal antibody directed against the IL-6 receptor that has established benefit in RA both with regards to clinical efficacy and ...

The U.S. Food and Drug Administration is replacing animal testing with human-relevant methods, including artificial ...

The randomized, double-blind, placebo-controlled trial aims to assess the safety, tolerability, and efficacy of intranasal foralumab in patients with na-SPMS, a form of multiple sclerosis (MS) ...