This study focuses on assessing the impact of aging on epithelial Cl − secretion in human colon mucosa through the measurement of short ... serosa-side bath solution to assess the never-mediated basal ...

Novo Nordisk’s bid to provide a once-weekly basal insulin product for people with diabetes, reducing the number of injections needed, has hit a major hurdle in the US. The FDA sent the Danish ...

Although nicotine appears to be the beneficial ingredient, the precise mechanism of action remains unclear. As the cause of ulcerative colitis remains unknown there is much opportunity for ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Maternal stress is a major risk factor for ...

In animal studies, IL-33 expression was upregulated in the CRSwNP group compared with controls. Anti-IL-33 treatment reduced the thickness of oedematous mucosa, subepithelial collagen deposition, and ...

Expert Rev Clin Pharmacol. 2009;2(3):295-314.

Objective Integration of nutritional, microbial and inflammatory events along the gut-brain axis can alter bowel physiology and organism behaviour. Colonic sensory neurons activate reflex pathways and ...

1 Laboratory for Immunohistochemistry and Immunopathology (LIIPAT), Institute of Pathology, and Department of Surgery, University of Oslo, Rikshospitalet, Oslo, Norway 2 Laboratory for ...

Correspondence to: Dr J M Wardlaw Division of Clinical Neurosciences, Western General Hospital, Crewe Rd, Edinburgh EH4 2XU UK; joanna.wardlawed.ac.uk If you wish to reuse any or all of this article ...