Mitochondria play a crucial role in acquiring pluripotency and determining cell fate. The mitochondrial unfolded protein ...

Kundu and James Clement, found that in mice with mutated syngap gene (Syngap1+/- mice) which resembles humans with mutated syngap gene (present in autistic patients) the acetylation of DNA ...

The Senate Environment and Public Works Committee held a hearing to examine the implementation of the 2021 Infrastructure Investment and Jobs Act. Several topics were addressed, including funding ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Corneal diseases can cause severe visual ...

Acetylation is a chemical modification that can be placed on and removed from the cable drum like a plug, causing changes in gene expression without changing the DNA sequence itself. Thus ...

Acetylation is a chemical modification that can be placed on and removed from the cable drum like a plug, causing changes in gene expression without changing the DNA sequence itself. Thus ...

Here we show that SARS-CoV-2 mRNA vaccination significantly establishes histone H3 lysine 27 acetylation (H3K27ac) at promoters of human monocyte-derived macrophages, suggesting epigenetic memory.

Acetylation of non-histones, including tumor suppressors and oncogenes (i.e., p53, Rb, and Myc), regulates protein stability, DNA binding, protein interactions, enzyme activity, or protein ...

Here we present CHAS (cell type-specific histone acetylation score), an R package for the cell deconvolution of bulk brain H3K27ac profiles. CHAS is split into two independent algorithms. In the first ...

A look at the people and events that shaped the Civil War and Reconstruction. Covering American History C-SPAN style: with event coverage, eyewitness accounts, and discussions with authors ...