Rationale and study design of the KOV-HIPEC-04: A phase III randomized controlled trial in primary stage three and four ovarian cancer after interval cytoreductive surgery (FOCUS).

Citing a “new evidenced based philosophy,” the FDA’s Center for Biologics Evaluation and Research (CBER) is preparing to take ...

Glycomine Initiates Dosing in a Global, Randomized, Placebo-Controlled Phase 2b Study of GLM101 for the Treatment of PMM2-CDG ...

For AI tools making high-stakes clinical decisions, well-designed, prospective RCTs must be the gold standard.

A cluster-randomized design was chosen because the intervention was implemented hospital-wide; a crossover design was chosen to improve the power and statistical efficiency of the trial.

Randomized control trials are the most rigorous way of determining whether a cause-effect relationship exists between treatment and outcome and assessing a treatment’s cost-effectiveness.