A new mouse model with a diverse microbiome may help scientists in their quest to make meaningful discoveries in mice that will translate well in humans.

Mouse models of prostate cancer Our laboratory is interested in the use of mouse models of prostate cancer to explore the pathogenesis of prostate cancer and its response to treatment. We have used ...

In mouse models, these changes tended to resolve within a couple of days. Not only did the individual genes that respond to inflammation differ across the species, so did the major pathways for ...

More clinically relevant mouse models for neurodegenerative diseases are sorely needed as tools to study disease progression and to develop future therapeutics. At last month's virtual International ...

A simple inbred rodent became one of the most important—and flawed—subjects in the history of science. Next up for the lab mouse: helping to reprogram the human genome.

With the rise of the modern lab mouse, the lumpers have come to dominate; their favorite tool was designed from the start to obscure the differences of things and champion their resemblances.

The first complete activity map of the brain has been unveiled by a large international collaboration of neuroscientists. The ...

Pain and sleep disturbances often go hand in hand—more than 30% of the U.S. population lives with pain, and a majority of ...

Coronavirus researchers need the right genetically engineered mice to test potential vaccines. But most of these mice have been on ice. One lab is breeding a new generation of mice to meet the demand.