Switching from an SSRI to an SNRI typically involves gradually tapering off the SSRI under a doctor’s guidance and starting the SNRI at a low dose. Switching from a selective serotonin reuptake ...

Antidepressants: the most common prescription medication among cool people like artists, fictional type As, film protagonists and yourself. If you’ve been diagnosed with depression, your healthcare ...

Researchers analysed and then meta-analysed data from two register-based, nationwide cohort studies in Finland (1996-2017) and Sweden (2006-2023) and included 23,206 patients with schizophrenia (mean ...

Esketamine combined with a serotonin-norepinephrine reuptake inhibitor (SNRI) for treatment-resistant depression (TRD) was linked to significantly lower rates of several adverse outcomes than ...

Among most ischemic (clot-caused) stroke survivors including those taking anticoagulant medications, use of antidepressants in the SSRI or SNRI class did not increase the risk of hemorrhagic (bleeds) ...

The absolute risk of AMD was low across all groups. The authors noted limitations to their study, such as possible unreliability of data, the possibility that cases of AMD were missed, and the lack of ...

Both severe depression and treatment-resistant depression are common. Up to one third of patients do not respond to conventional therapy with antidepressants such as selective serotonin reuptake ...