New research has advanced understanding of how the nucleolus is assembled through a process called liquid-liquid phase separation and has identified a protein that plays key role Researchers have ...

Biologists discovered that a scaffolding protein called TCOF1 is responsible for the formation of a biomolecular condensate called the fibrillar center, which forms within the cell nucleolus. Inside ...

Striking nucleolar lesions occur in cultured cells after exposure to supranormal temperatures. These lesions appear at 42°C and consist of a loss of the granular ribonucleoprotein (RNP) component and ...

The nucleolus is a well-known cellular structure that is easily visible under a light microscope. This nuclear structure is known as the site of ribosome production. In a recent study, researchers at ...

The secret to cellular youth may depend on keeping the nucleolus—a condensed structure inside the nucleus of a cell—small, according to Weill Cornell Medicine investigators. The findings were ...

THE nucleolus was first figured in 1781 as a spot in the centre of a round or oval body (the nucleus) in epithelial cells of the eel. Since then it has been described in the nuclei of almost every ...

Ageing researchers have long been searching for so-called biomarkers of ageing, which allow predictions about health and lifespan of organisms. Varnesh Tiku, a scientist in the department of Director ...

Keeping nucleoli small prevents DNA instability and cellular aging, akin to anti-aging effects like calorie restriction Nucleolar expansion marks a tipping point in aging, acting as a "mortality meter ...

Inside all living cells, loosely formed assemblies known as biomolecular condensates perform many critical functions. However, it is not well understood how proteins and other biomolecules come ...

Inside all living cells, loosely formed assemblies known as biomolecular condensates perform many critical functions. However, it is not well understood how proteins and other biomolecules come ...