The five phases of mitosis and cell division tightly coordinate the movements ... The composition of the spindle fibers remained unknown until the 1960s, when tubulin was discovered and techniques ...

In an article published in the journal PLoS Computational Biology, scientists used a data science approach to study the variations observed between different cells in spindle formation. This ...

Cell division allows a single fertilized egg to ... of the cell with the help of molecular "pulling ropes"—called the spindle apparatus—aligned next to each other, and finally pulled to ...

HDAC6 is upregulated in corneal diseases and causes ENKD1 deacetylation at lysine 98. Deacetylation of ENKD1 blocks its ...

Michael Lampson, PhD is a cell biologist at the University of Pennsylvania. His research group focuses on cell division, centromere function in the germline, and the cell biology of meiotic drive.

During cell division, mitosis refers specifically to ... A large structure called the mitotic spindle also forms from long proteins called microtubules on each side, or pole, of the cell.

About 100 cells divide every second in our body. A key protein in cell division is a protein kinase termed Plk1, because it activates other proteins involved in this process. Plk1 is also ...