SMFS allows the direct measurement of the strength and kinetics of receptor-ligand interactions at the single-molecule level. By attaching a receptor to a surface and a ligand to a force probe, the ...

Using single-molecule force spectroscopy, the authors demonstrate that proline isomerization and cysteine-mediated disulfide bonds lead to distinct mechanical states of the titin I-band ...

At the Berlin synchrotron radiation source BESSY II, the largest magnetic anisotropy of a single molecule ever measured ... electron paramagnetic resonance spectroscopy (THz-EPR) at the ...

11/2023: Xiangcheng was invited to write a Behind-the-Paper post at Springer Nature, Chemistry Community. The post appears "Single-molecule fluorescence imaging and sequencing of single synthetic ...

The flexible nanogap structures developed in this research serve as a key component in Surface-Enhanced Raman Spectroscopy ... suitable for single-molecule detection. Dr. Mahsa Haddadi Moghaddam ...

We utilize design, synthesis, and spectroscopy for tailoring fundamental properties of nanoscaled materials for energy harvesting and novel therapeutics, and developing new spectroscopic techniques ...

We are also refining and applying ultrahigh-resolution spectroscopy techniques to dissect multistep complex biochemical processes using in vitro reconstituted single-molecule assays. Jieru Li, Ankun ...

Nuclear magnetic resonance (NMR) spectroscopy is a technique that ... protein domain is investigated by integrating NMR, single-molecule FRET and MD simulations. Net charge and charge ...

Proton transfer in aqueous systems is a fundamental process occurring constantly around us. It involves a molecule losing a ...

The flexible nanogap structures developed in this research serve as a key component in Surface-Enhanced Raman Spectroscopy (SERS ... a detection limit as low as 10⁻¹² M, suitable for single-molecule ...