Covariate-adaptive randomization represents an advanced methodology in the design of clinical trials, ensuring a balanced distribution of prognostic factors among treatment groups. This approach ...

When REDCap did not offer a way to use covariate-adaptive randomization algorithms (CARAs), researchers realized they would ...

The World Health Organization recommends 1500 to 2000 mg of calcium daily as supplementation, divided into three doses, for pregnant persons in populations with low dietary calcium intake in order to ...

Treatment for patients with recurrent ovarian cancer has been mainly based on systemic therapy. The role of secondary cytoreductive surgery is unclear. We randomly assigned patients with recurrent ...

We are witnessing an increasing demand for rapid, rigorous, and generalizable evidence to inform health care systems’ learning and address inefficiencies in the current clinical trials landscape.

For more than three decades, researchers Christine Stabell Benn and Peter Aaby from the Bandim Health Project have conducted ...