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A more effective treatment for aggressive breast cancer: Two inhibitor drugs show potential
The findings are in the article, "NOS inhibition sensitizes metaplastic breast cancer to PI3K inhibition and taxane ... aggressive and difficult-to-treat subtypes of breast cancer," said Chang.
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Exploiting the PI3K/AKT Pathway for Cancer Drug Discovery
The phosphatidylinositol-3-kinase (PI3K) pathway plays a crucial role in cell growth and survival and is activated in various cancers. Multiple components of the pathway are frequently targeted by ...