F or the first time, researchers have fused two mouse chromosomes together in vitro, resulting in living mice with new karyotypes. The new technique, detailed in a study published today (August 25) in ...

Males imprint their DNA by adding methyl modifications to it in a way that alters the activity of genes in order to promote ...

We're a step closer to two men being able to have genetic children of their own after the creation of fertile mice by putting ...

Evolutionary chromosomal changes may take a million years in nature, but researchers are now reporting a novel technique enabling programmable chromosome fusion that has successfully produced mice ...

The accurate distribution of chromosomes in an oocyte is essential for the correct transmission of genetic information to the ...

M ice with two fathers have, for the first time, gone on to have babies of their own, showing that mice created with two ...

The laboratory mouse has a standard karyotype of 40 chromosomes. This consists of 19 pairs of autosomes plus the X and Y chromosomes. Engineering large-scale changes to this set has been ...

By the age of 70, about 40% of men have lost the Y chromosome in at least some of their white blood cells. This condition, ...

The first mice to be created from two fathers, a phenomenon known as androgenesis, have now produced healthy offspring for ...

Reporting on their findings in Nature, “The maternal X chromosome affects cognition and brain aging in female mice,” co-senior author Dubal and colleagues concluded, “Understanding how X m ...

Scientists have created mice with two biologically male parents for the first time — a significant milestone in reproductive biology.

A study of mice might explain why. By Gina Kolata It’s been known for more than half a century that many men lose their Y chromosomes as they age. But no one knew if it really mattered. The loss ...