For the first time, researchers have fused two mouse chromosomes together in vitro, resulting in living mice with new karyotypes. The new technique, detailed in a study published today (August 25) in ...

Females have one active X chromosome and one dormant X chromosome in each cell. But a study suggests that genes on the ...

The team knocked out the chromosome in mice’s bone marrow cells by deleting its centromere with CRISPR, mirroring the degeneration of the Y chromosome in male humans. The modification successfully ...

Scientists discover that women's second X chromosome awakens later in life, expressing genes that protect the brain from aging.

Researchers at the Crick have uncovered which genes on the Y chromosome regulate the development of sperm and impact fertility in male mice. This research could help us understand why some men don ...

On Tuesday, the team behind the plan to bring mammoth-like animals back to the tundra announced the creation of what it is ...

Females carry two X chromosomes. One of them is ensconced in a corner in the cell called the Barr body, where it can’t express many genes, and scientists thought it didn’t do much of anything. But the ...

As shown in Figure 4, regions on the arms of mouse chromosomes 10 (MMU10), 16 (MMU16), and 17 (MMU17) are syntenic with regions on the long q arm of human chromosome 21. Using some genetic tricks ...

One way to understand the function of a gene is to observe a biological system that lacks that gene. But what is the best system to use? When studying human genes, researchers typically employ ...

In a surprise, work in mice has found that the dormant X chromosome in females can reawaken late in life and turn on genes that keep the brain healthy. UCSF researchers may have discovered how the ...

The scientists created hybrid mice from two different strains of laboratory mouse and engineered the X chromosome from one strain to be silent. Since they knew the genetic code for each strain ...