F or the first time, researchers have fused two mouse chromosomes together in vitro, resulting in living mice with new karyotypes. The new technique, detailed in a study published today (August 25) in ...

Evolutionary chromosomal changes may take a million years in nature, but researchers are now reporting a novel technique enabling programmable chromosome fusion that has successfully produced mice ...

Males imprint their DNA by adding methyl modifications to it in a way that alters the activity of genes in order to promote ...

The first mice to be created from two fathers, a phenomenon known as androgenesis, have now produced healthy offspring for ...

We're a step closer to two men being able to have genetic children of their own after the creation of fertile mice by putting two sperm cells in an empty egg ...

The laboratory mouse has a standard karyotype of 40 chromosomes. This consists of 19 pairs of autosomes plus the X and Y chromosomes. Engineering large-scale changes to this set has been ...

The accurate distribution of chromosomes in an oocyte is essential for the correct transmission of genetic information to the ...

How did they create mice with two dads? The scientists put two mouse sperm cells into a mouse egg which had been emptied of ...

Reporting on their findings in Nature, “The maternal X chromosome affects cognition and brain aging in female mice,” co-senior author Dubal and colleagues concluded, “Understanding how X m ...

Scientists have created mice with two biologically male parents for the first time — a significant milestone in reproductive biology.

Old female mice had more PLP1 in the hippocampus than old male mice, suggesting that the extra PLP1 from the second X chromosome had made a difference. To test whether PLP1 could explain the ...