The DNA repair and replication pathways converge on a common final step in which the continuity of the repaired DNA strand is restored by DNA ligase, an enzyme that converts nicks into phosphodiester ...

After two fragments with complementary sticky ends are joined, the DNA backbone may be covalently sealed using another enzyme called DNA ligase.

The breaks are caused by a variety of things, including normal cellular processes like DNA replication ... knock-on effects ...

A few years ago, the advent of technology known as CRISPR was a major breakthrough in the scientific world. Developed from a ...