A life-saving treatment of IV ketamine could reverse suicidal depression. It might be approved by the FDA and administered by ...

A major Cochrane review found no convincing evidence that ketamine or similar NMDA-blocking drugs improve chronic non-cancer ...

A sweeping review of 67 trials has cast doubt on the use of ketamine and similar NMDA receptor antagonists for chronic pain relief. While ketamine is frequently prescribed off-label for conditions ...

An extensive analysis shows scant evidence that ketamine or other NMDA receptor agonists reduce chronic noncancer pain but ...

The off-label use of ketamine to treat chronic pain is not supported by scientific evidence, a new Cochrane review has found. Ketamine is an anaesthetic commonly used for procedural sedation and short ...

A strong anesthetic ‘Ketamine’ is normally used in hospital procedures. Ketamine is also used for short-term pain management in hospitals. It works by blocking a brain signal ...

A Cochrane review assessed ketamine and other NMDA receptor antagonists for chronic non-cancer pain. The evidence was low to very low certainty, showing no clear pain relief and potential adverse ...

Researchers cautioned that the existing evidence base is too poor to draw any solid conclusions on whether ketamine can help ...

They tested different concentrations of ketamine and its enantiomers, ranging from 0.002 to 10 microMolar, and examined how various mutations in the receptor affected ketamine’s ability to ...

NMDA receptor antagonists are a group of medicines that affect the excitability of nerves involved in pain and other brain functions. They include ketamine, memantine, dextromethorphan, amantadine, ...

Ketamine, a non-competitive N-methyl-D-aspartate receptor antagonist, has emerged as an effective therapeutic agent for the management of treatment-resistant depression. Repeated treatments with ...

Ketamine primarily acts as an NMDA, a glutamate receptor, receptor antagonist. The NMDA receptor system is a complex of proteins in the brain that plays a crucial role in synaptic plasticity ...