Information about environmental stimuli is often transmitted using common signaling molecules, but the mechanisms that ensure signaling specificity are not entirely known. Here we show that the ...
Tumor necrosis factor receptor–associated factors (TRAFs) are a recently established group of proteins involved in the intracellular signal transduction of several members of the tumor necrosis factor ...
Please provide your email address to receive an email when new articles are posted on . The novel gene therapy SPK-8011 induced sustained factor VIII expression in patients with hemophilia A, ...
The goal of gene therapy for patients with hemophilia A is to safely impart long-term stable factor VIII expression that predictably ameliorates bleeding with the use of the lowest possible vector ...
Expression of the retinoblastoma-related gene Rb2/p130 correlates with clinical outcome in endometrial cancer. The ratio of integrin alpha3/beta-actin expression ranged from 0 to 5.87 (mean was 0.80; ...
Announcing a new article publication for Cardiovascular Innovations and Applications journal. This paper describes the expression profiles and roles of cardiac pigment epithelium-derived factor (PEDF) ...
The angiotensin-converting enzyme 2 (ACE2) has been identified as the major functional site facilitating binding and host-cell entry of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).