Case-control studies are among the most commonly used means of assessing association between exposure and outcome. Sample size determination and the optimal control-to-case ratio are vital to the ...

Shortcomings in study design and errors in genotype calling have the potential to introduce systematic biases into genetic case-control association studies, leading to an increase in the number of ...

For a desired power of detecting the association between a disease and several potential risk factors in case-control studies, Yang (1978, Biometrika 65, 635-640) and Halperin (1980, Biometrika 67, ...

In a nationally representative sample of 1.1 million homes, we compared the prevalence of smoking among 33,000 deceased women and 41,000 deceased men (case subjects) with the prevalence of smoking ...