I sent $3.99 to Epson about 6 weeks ago to participate in their program that promised OS X drivers for their scanners--in my case, the Epson 1250 Perfection. Today, I received my first response.

In modern incarnations of Linux -- especially Ubuntu -- most scanners work when plugged in via USB. Many Epson printers work on Linux without the need of additional drivers, but you can also ...

I finally received my Epson Perfection 2450 Photo yesterday. Quite pleased with it. I had figured that there wouldn't be any OsX support and I would have to rely on VueScan (which functioned, but ...

The Epson TWAIN seems actually to work better with Photoshop than it's own Scan-to-File application." Update: Also see this MacFixIt Forums Thread, which discusses similar success with an Epson ...