Researchers have made a significant advance toward the goal of using bacteria—rather than fossil fuels—to produce ethylene, a ...

CHAMPAIGN, Ill. — A new artificial intelligence tool can predict the functions of enzymes based on their amino acid sequences, even when the enzymes are unstudied or poorly understood. The researchers ...

Researchers participating in the Enzyme Function Initiative (EFI) have used a computationally rich metabolite-docking strategy to sift through a protein’s potential metabolic partners and predict its ...

COLLEGE STATION, Nov. 6, 2007 – Fitting a key into a lock may seem like a simple task, but researchers at Texas A&M University are using a method that involves testing thousands of keys to unlock the ...

Cytochrome P450 enzymes constitute a superfamily of haem-containing proteins that catalyse the oxidation of a wide range of exogenous and endogenous compounds. Their function is fundamental to the ...

In this corner: the state-of-the-art enzyme function prediction tool … the Bioinformatic Brawler … the Basic Local Alignment Search Tool for proteins … BLASTp! And in this corner: the contender … the ...

All life on Earth is unified by its use of a shared set of component chemical compounds and reactions, providing a detailed model for universal biochemistry. However, this notion of universality is ...

Patients with lupus are at increased risk of heart disease. Exposing endothelial cells -- known to protect against heart disease, in part by producing nitric oxide -- to the serum of patients with ...

Annotations of enzyme function provide critical starting points for generating and testing biological hypotheses, but the quality of functional annotations is hindered by uncertain assignments for ...

Scientists have found a novel way of monitoring individual enzymes as they chomp through fat. The method offers far greater insight into how enzymes function and opens up the possibility of tailoring ...

Researchers at Baylor College of Medicine and collaborating institutions report in the journal Nature Communications how a mutation in the enzyme SKD3 can cause a form of a genetic disease known as ...