A new AI tool reveals how tangled DNA knots impact health and disease, offering insights for drug discovery and genetic ...

Unexpected slowdowns or spikes in this signal were often interpreted as knots in DNA. But now, a new study published Aug. 12 ...

By creating a more true-to-life representation of DNA's environment, researchers have discovered that strand separation may take more mechanical force than the field previously believed.

DNA doesn’t knot under stress. A new study finds it coils into plectonemes, reshaping models of genome mechanics. For decades ...

By creating a more true-to-life representation of DNA's environment, researchers at Northwestern University have discovered that strand separation—the essential process a "resting" double helix ...

The technique uses a long strand of DNA with a set sequence—the template—and a bunch of shorter, premade DNA molecules that can base pair with specific spots on the template—the bricks.

By creating a more true-to-life representation of DNA's environment, researchers at Northwestern University have discovered that strand separation - the essential process a "resting" double helix ...

They are called plectonemes. They are the analog of the twisted tangles of telephone cords, and can form in DNA that is pulled through a nanoscale channel. This is the finding of a study led by Ulrich ...

Lead author of "Distinct regulation of ATM signaling by DNA single-strand breaks and APE1," Haichao Zhao offered that the research may support future clinical trials – both for attacking cancer ...