Scientists have uncovered a surprising mechanism by which a brain enzyme called OTULIN controls the expression of tau, the ...

All the cells in an organism have the exact same genetic sequence. What differs across cell types is their ...

Gene regulation is the process by which cells control the expression of their genes, determining when, where, and to what extent each gene is expressed. It is a fundamental mechanism that allows cells ...

With a new study in the journal Cell, researchers at Stanford University and Stockholm University have contributed to ...

New research has shown that the enzyme OTULIN regulates tau at the gene-expression level rather than through protein ...

A figure from the paper illustates a key finding of "compromised compartmentalization": chromatin that was locking genes down in health became more open in Alzheimer's, while chromatin that was open ...

HOUSTON, NOVEMBER 24, 2025 ― Researchers at The University of Texas MD Anderson Cancer Center have shown that DNA inflexibility, or rigidity, inside ...

Citrullination, a transformative protein post-translational modification, is gaining recognition for its wide-ranging impact on cellular function and human disease. This process, driven by the enzyme ...

To help achieve more precise control of gene therapy, engineers have designed a new control circuit that can keep gene expression levels within a target range. The method could be used to deliver ...