A research team from the University of Oklahoma has pioneered a method that could accelerate drug discovery and reduce pharmaceutical development costs. Their work, published in the Journal of the ...

Researchers have used single carbon atom doping to form four chemical bonds in one step. Gamma-lactams (cyclic molecules that are common in antibiotics) were easily synthetically accessible from alpha ...

Together, the two methods should enable medicinal chemists to make these single-atom substitutions in a swath of common molecules, easing efforts to generate analogues of drug candidates. “This is the ...

Despite its stability and abundance on Earth and in the wider Universe, carbon is an element for which little is known about the liquid state 1. This is mainly because carbon evaporates directly at ...

Adding a carbon atom in the late stages of development can make new drugs cheaper. It's like renovating a building rather than building it from scratch," Sharma said. "By making these drugs easier to ...