The new body-horror movie "The Substance" is a wild time, It also took co-stars Demi Moore and Margaret Qualley way out of their comfort zones.

We felt like we knew each other,” Demi Moore tells PEOPLE of Margaret Qualley, her costar in Coralie Fargeat’s horror movie Demi Moore and Margaret Qualley had a personal connection offscreen long before sharing one onscreen in their new movie The Substance.

"The Substance" is a dark modern fable that starts out blaming men for reducing women to sex objects and then cuts deeper. Fargeat saves a special rage for women who conspire in their own diminishment, trading their soul in a pulse beat for a few more shining hours as a goddess.

The actress stars alongside Margaret Qualley and Dennis Quaid in Coralie Fargeat’s gleefully grotesque movie about an aging celebrity who takes an experimental drug that gives her a younger self.

She and costar Margaret Qualley also devoted time to perfecting sexualized gyrations their celebrity fitness characters would perform in front of leering cameras and a slimeball of a boss, played by Dennis Quaid,

The Substance, the new film starring Margaret Qualley and Demi Moore, has set a record for the latter. The body-horror film follows a fading celebrity (played by Moore) who begins to use a black-market drug that creates a younger version of herself (Qualley).